In Stock Pharmaceutical Intermediate Powder Pimobendan 74150-27-9

Quick Details:

Name:Pimobendan 

CAS:74150-27-9 

Quality Standard: USP32/BP2007/EP7 

Apperance: White Powder

[Mol. Formula ] C19H18N4O2

Packaging Detail: 

100g/bag,500g/bag,1kg/bag,25kg/drum

Usage:

Pimobendan is used in the management of heart failure in dogs, most commonly caused by myxomatous mitral valve disease (also known as endocardiosis), or dilated cardiomyopathy.Research has shown that pimobendan increases survival time and improves quality of life in patients with congestive heart failure secondary to mitral valve disease when compared with benazepril, an angiotensin-converting-enzyme (ACE) inhibitor.

Reference FOB Price:$1/g

MOQ:10g

Specification:ISO9001,USP,BP,GMP

Trade Mark:CQSP

Port:Shenzhen/Shanghai,China

Production Capacity:5000kg/month

More details pls contact:Whatapp:86 13048470428  

 Skype/E-mail : summer at chembj.com

Usage:

Pimobendan is used in the management of heart failure in dogs, most commonly caused by myxomatous mitral valve disease (also known as endocardiosis), or dilated cardiomyopathy.Research has shown that pimobendan increases survival time and improves quality of life in patients with congestive heart failure secondary to mitral valve disease when compared with benazepril, an angiotensin-converting-enzyme (ACE) inhibitor

COA

Item Specifications Results

Appearance White or slightly yellowish Powder Slightly yellowish

solubility Practically insoluble in water, freely soluble in dimethylformamide, slightly soluble in acetone and in methanol. Conforms

Identification Infrared absorption spectrophotometry , Comparison pimobendan CRS Conforms

Heavy metals ≤10ppm 1ppm

Water ≤1.0% 0. 1%

Assay (HPLC) 98.0%~100.0% 99.83%

Sulphated ash ≤0.1% 0.01%

Related substances(HPLC) Impurity A:≤0.1% 0.03%

Impurity B:≤0.1% 0.07%

Any other impurity:≤0.1% 0.05%

Total impurity:≤0.2% 0.17%

Conclusion The results conforms with Enterprise standards

Pimobendan

Pimobendan is mainly used in the management of heart failure in dogs, most commonly caused by myxomatous mitral valve desease (also previously known as endocardiosis), ordilated cardiomyopathy. 

Specification

 Pimobendan , its cas register number is 74150-27-9. It also can be called Pimobendane ; dl-Pimobendan ; and 4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-3(2H)-pyridazinone . It is a positive inotrope, and sensitizes and increases the binding efficiency of cardiac myofibril to the calcium ions that are already present without increasing the consumption of oxygen and energy. It is metabolized into its active form by the liver, and is absorbed rapidly when given via the oral route and has a bioavailability of 60-65%.