99.5% API Sevelamer Hydrochloride Renagel (Sevelamer HCl) CAS 152751-57-0

Basic Info.

Product Name: Sevelamer hydrochloride

Synonyms:SEVELAMER HCL;Sevelemar;Sevelamer Hydrochloride;2-Propen-1-amine polymer with (chloromethyl)oxirane hydrochloride;(ChloroMethyl)oxirane polyMer with 2-Propen-1-aMine Hydrochloride;2-Propen-1-aMine Hydrochloride polyMer with 2-(ChloroMethyl)oxirane;AllylaMine Hydrochloride-epichlorohydrin CopolyMer;SevelaMer HCL API

CAS RN.:   152751-57-0

EINECS:    244-759-8

Molecular Weight:    149.61858

Molecular Formula:   C6H12ClNO

Density:    152751-57-0.mol

Purity:99.5%

Package:25kg/barrel 

Reference FOB Price:$0.12/g

MOQ:1kg 

Specification:ISO9001,USP,BP,GMP

Trade Mark:CQSP

Port:Shenzhen/Shanghai,China

Production Capacity:5000kg/month

Delivery time: 3~7 working days

Payment methods: T/T, Western Union, Moneygram, Bitcoin

More details pls contact:Whatapp:86 13048470428  

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Description:

Sevelamer (rINN) is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease. When taken with meals, it binds to dietary phosphate and prevents its absorption. Sevelamer was invented and developed by GelTex Pharmaceuticals.

Sevelamer is currently marketed by Sanofi under the trade names Renagel (sevelamer hydrochloride) and Renvela (sevelamer carbonate).

Usage:

Sevelamer is used to lower high blood phosphorus (phosphate) levels in patients who are on dialysis due to severe kidney disease. Dialysis removes some phosphate from your blood, but it is difficult to remove enough to keep your phosphate levels balanced. Decreasing blood phosphate levels can help keep your bones strong, prevent unsafe buildup of minerals in your body, and possibly decrease the risk of heart disease and strokes that can result from high phosphate levels. Sevelamer works by holding onto phosphate from the diet so that it can pass out of your body.

Overview:

Sevelamer therapy is contraindicated in hypophosphatemia or bowel obstruction. In hypophosphatermia, sevelamer could exacerbate the condition by further lowering phosphate levels in the blood, which could be fatal.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Sevelamer may interfere with the effectiveness of some drugs (including mycophenolate, thyroid medications such as levothyroxine, among others) by making it more difficult for them to be absorbed by the stomach. Ask your pharmacist about the best times to take your other medications