Supply High Quality Pharmaceutical Raw Material 99% Griseofulvin CAS:126-07-8 

Quick Details 

Product Name:(+)-Griseofulvin

CAS:126-07-8

MF:C17H17ClO6

MW:352.77

EINECS:204-767-4

Product Categories:Intermediates & Fine

Purity:99%

Chemicals;Pharmaceuticals;Antifungal;Aromatics;Chiral Reagents;VERELAN

Chemical Properties:Crystalline Solid

Package:20kg/barrel or as your inquiry 

Shelf life:2 years

Standard:Enterprise Standard 

Price:negotiable 

MOQ:10g

Specification:ISO9001,USP,BP

Trade Mark:CQSP

Shipping: DHL, EMS, FedEx, UPS

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Usage:

1) adrenegic blocker, Ca channel blocker, coronary vasodilator, antiarrhythmic

2) antifungal, inhibits mitosis in metaphase

3) Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect of the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy.

4) It is an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum

Medical uses

Griseofulvin is used orally only for dermatophytosis. It is ineffective topically. It is reserved for cases with nail, hair, or large body surface involvement.

Pharmaceutical raw materials   An anti-fungal and anti-proliferative agent that affects microtubules

Griseofulvin, an antifungal agent, has been reported to inhibit proliferation of various types of cells. This compound has also been shown to strongly suppress the dynamic instability of individual microtubules via reduction of the rate and extent of the growing and shortening phases. The effects that Griseofulvin has on microtubules can cause mitotic arrest and abnormalities, such as multipolar spindles, misaligned chromosomes, and fragmented nuclei.

Application for Griseofulvin

1) Griseofulvin is an antifungal drug that is administered orally. It is used both in animals and in humans, to treat fungal infections of the skin (commonly known as ringworm) and nails. 

2) Potential for cancer treatment   

3) Griseofulvin is used orally only for dermatophytosis