Pharmaceutical Grade Bilirubin CAS No.: 635-65-4

Basic Views

Name:Bilirubin

EINECS NO.: 211-239-7

CAS No.: 635-65-4

Molecular Formula: C33H36N4O6

Molecular Weight: 584.67

Assay: 99% min HPLC

Appearance: red powder,easily soluble in ethanol,almost insoluble in water.

Melting point: 192ºC

Water solubility: insoluble

Shelf life:2 years

Standard:Enterprise Standard 

Price:negotiable 

MOQ:10g

Specification:ISO9001,USP,BP

Trade Mark:CQSP

Port:Shenzhen/Shanghai,China

Production Capacity:5000kg/month

Package:1kg/foil bag or as your inquiry

Shipping: FedEx, DHL, EMS, TNT, HK EMS, Eub, Etk

Introduction of Bilirubin

Bilirubin (formerly referred to as haematoidin and discovered by Rudolf Virchow in 1847 is a yellow compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates. This catabolism is a necessary process in the body's clearance of waste products that arise from the destruction of aged red blood cells. First the hemoglobin gets stripped of the heme molecule which thereafter passes through various processes of porphyrin catabolism, depending on the part of the body in which the breakdown occurs. For example, the molecules excreted in the urine differ from those in the feces. The production of biliverdin from heme is the first major step in the catabolic pathway, after which the enzyme biliverdin reductase performs the second step, producing bilirubin from biliverdin.

Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases. It is responsible for the yellow color of bruises and the yellow discoloration in jaundice. Its subsequent breakdown products, such asstercobilin, cause the brown color of feces. A different breakdown product, urobilin, is the main component of the straw-yellow color in urine.

It has also been found in plants.

Function

Bilirubin is created by the activity of biliverdin reductase on biliverdin, a green tetrapyrrolic bile pigment that is also a product of heme catabolism. Bilirubin, when oxidized, reverts to become biliverdin once again. This cycle, in addition to the demonstration of the potent antioxidant activity of bilirubin, has led to the hypothesis that bilirubin's main physiologic role is as a cellular antioxidant.

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