Anastrozole CAS 120511-73-1 Arimidex Medicine Injectable Anabolic Steroid Hormones 

Product Name: Anastrozole

Synonyms: ICI-D-1033;ARIMIDEX;1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4-TRIAZOLE;ANASTRAZOLE;ANASTROZOLE;tetramethyl-5-(1h-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile;ZD-1033;1,3-benzenediacetonitrile,alpha,alpha,alpha’,alpha’-tetramethyl-5-(1h-1,2,4-t

CAS: 120511-73-1

MF: C17H19N5

MW: 293.37

Product Categories: Active Pharmaceutical Ingredients;Antineoplastic;All Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Anastrozole;API

Mol File: 120511-73-1.mol

Anastrozole is an inhibitor for the triazole aromatase with a strong selectivity. It can inhibits aromatase which is prerequisite for the synthesis of pigment cells P-450 thereby blocking the biosynthesis of estrogens, and the estrogen is the essential part of the growth of breast cancer cells. The 50% inhibitory concentration (IC50) value of anastrozole to placental aromatase is 15nmol/L.

Letrozole is used for the treatment of advanced breast cancer of postmenopausal women.It mainly applied to the second-line treatment after the failure of the anti-estrogen treatment.

(1) It is the third-generation’s aromatase inhibitors, used for the treatment of advanced breast cancer of postmenopausal patients.

(2) Its used to cure the breast cancer.

(3) Anastrozole is the third-generation’s aromatase inhibitors, used for the treatment of advanced breast cancer of postmenopausal patients. It is an inhibitor for the triazole aromatase with a strong selectivity. It can inhibits aromatase which is prerequisite for the synthesis of pigment cells P-450 thereby blocking the biosynthesis of estrogens, and the estrogen is the essential part of the growth of breast cancer cells. Its used to cure the breast cancer, particularly suitable for postmenopausal women with advanced breast cancer who recrudescent after hormone adjuvant therapy.