99% Oral Reverse Transcriptase Inhibitor 142340-99-6 Adefovir Dipivoxil

Basic Info.

Product Name:Adefovir dipivoxil

Chemical Name:9-[2-[bis[(pivaloyloxy)methoxy]phosphinyl]methoxy]ethyl]adenine

CAS:142340-99-6

MF:C20H32N5O8P

MW:501.47

EINECS:200-001-8

Assay:99%min

Appearence:White to white crystalline powder.

Purpose:Adefovir dipivoxil with broad-spectrum antiviral activity, can be used for the treatment of chronic hepatitis B.

Package:1kg/bag.

Reference FOB Price:$1/g

MOQ:1kg

Specification:ISO9001,USP,BP,GMP

Trade Mark:CQSP

Port:Shenzhen/Shanghai,China

Production Capacity:5000kg/month

Usage:

Adefovir Dipivoxil(Preveon, Hepsera) works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. It is approved for the treatment of chronic hepatitis B in adults with evidence of active vir 

Adefovir dipivoxil Usage A nucleotide analog, useful as an oral reverse transcriptase inhibitor (ntRTI). 

COA:

Product name Adefovir dipivoxil

CAS No. 142340-99-6 Outer Packing 1kg/Aluminum foil bag

Production date 2016.05.29 Shelf life 2018.05.29

Standard adopted enterprise specifications

Items of analysis Specification Results

Appearance White power or off-white power Conforms

Solubility Conforms

Identification Must conform to reference standard(HPLC,UV,IR) Conforms

Loss on dring NMT 0.5% 0.27%

Heavy metal NMT 20ppm Conforms

single Impurity NMT 0.1% 0.06%

Total Impurity NMT 0.5% 0.26%

Mono-POM PMEA NMT 0.2% 0.13%

NMP NMT 4000ppm Conforms

Acetic ether NMT 1000ppm Conforms

Acetone NMT 1000ppm 158ppm

  NMT 1000ppm 216ppm

Chloromethyl NMT 1000ppm 116ppm

Melting Point 98 ~102°C 99.6~101.0°C

Assay NLT 99.5% 99.76%

Conclusion Qualified