Anti Estrogen Steroid Toremifene Citrate CAS 89778-27-8 for Cancer Treatment

Basic Views

Name:Toremifene Citrate 

Synonyms: FC 1157a; Fareston; NK 622; NSC 613680

CAS: 89778-27-8

Appearance: White or almost white powder

Purity:98%

Package: 5kg/barrel or as your inquiry 

Molecular Formula: C26H28ClNO·C6H8O7

Molecular Weight: 598.09

Melting Point: 158-164 ºC

Boiling Point: 535.1 ºC at 760 mmHg

Density: 1.045g/cm3

Refractive index: 1,416-1,418

Suitable for:Adult

HS code: 3001200010

Reference FOB Price:$1/g

MOQ:1kg

Specification:ISO9001,USP,BP,GMP

Trade Mark:CQSP

Production Capacity:5000kg/month

Shelf life:2 years

Shipping: DHL, EMS, FedEx, UPS

Payment: Western Union, Moneygram, T/T, Bitcoin

Delivery time: Parcel can be sent out within 24hours after your payment, 4~7 days to arrive.

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Descriptions of Toremifene Citrate 

Fareston will display both estrogen antagonist / agonist properties in the body. This puts Fareston in the same category as Nolvadex and Clomid, the two most popular drugs in Farestons category. FARESTON is an estrogen agonist/antagonist indicated for the treatment of metastatic breast cancer in postmenopausal women with estrogen-receptor positive or unknown tumors.

Toremifene administration for a period of 3 months in men with idiopathic oligozoospermia is associated with significant improvements of sperm count, motility, and morphology, mediated by increased gonadotropin secretion and possibly a direct beneficial effect of toremifene on the testes. The above findings are also indicative of a better testicular exocrine (improved sperm parameters) response to treatment in men whose partners achieved pregnancy compared with those who did not. Further randomized, placebo-controlled trials should be conducted to determine whether this particular selective estrogen receptor modulator can be useful as an initial approach in men with oligozoospermia.

Applications:

Toremifene Citrate improved lipid profiles, particularly as an enhancer of high density lipoprotein cholesterol. it improved low density lipoprotein cholesterol levels.Both fareston and tamoxifen selective estrogen receptor modulators and equivalent treatments for metastatic breast cancer.No significant differences were found between treatment with either tamoxifen or fareston Treatment of HR-positive patients with either tamoxifen or toremifene is appropriate.In treating idiopathic oligozoospermia, tamoxifen and fareston are roughly equally effective but raloxifene is not.The antiestrogenic effects of SERMs at the hypothalamic level result in a statistically significant increase of gonadotropin levels, which is more marked for tamoxifen and fareston compared with raloxifene