99% Pure Effective Pharmaceutical Raw Materials CAS 76-25-5 Triamcinolone Acetonide

Basic Info.

Product name: Triamcinolone acetonide

Alias: Triamcinolone acetonide

CAS No.: 76-25-5

EINECS: 200-948-7

Molecular formula: C24H31FO6

Molecular weight: 434.5

Appearance: White crystalline powder

Assay: 99%

Package:1kg/foil bag 

Usage: neurodermatitis, eczema, psoriasis, joint pain, bronchial asthma and other illnesses.

Reference FOB Price:$20/g

MOQ:10g

Trade Mark:CQSP

Production Capacity:5000kg/month

Shipping: DHL, EMS, FedEx, UPS

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Description :

Triamcinolone acetonide is a kind of long-term glucocorticoid drugs which is now widely used in clinical Dermatology of China . It belongs to adrenocorticotropic hormone drugs. It is the derivative of Triamcinolone , and with the same function as Triamcinolone . Triamcinolone acetonide functions in anti-inflammatory , anti-allergic , anti-itching and shrinking capillaries. What's more , besides its weak water-sodium retention , the effect of Triamcinolone acetonide for anti-inflammatory , anti-allergic is much stronger and more durable than hydrocortisone (10 to 30 folds) , and prednisone . It can also treat bronchial asthma by aerosol inhalation with very strong and durable effect . Triamcinolone acetonide has better efficacy on local treatment compared with triamcinolone as glucocorticoid steroids .

Application :

It is Oral absorbed easily . Taking orally 5mg of the drug yields a bioavailability of about 23% . Its plasma concentration reaches peak (105 ng/mL) within one hour with the half-life is being 2 hours ; It has a slow intramuscular absorption rate which takes effect within hours , and gives maximal effect within 1 to 2 days . The effect can be maintained for 2 ~ 3 weeks ; the absorption rate of intradermal and intra-articular injection of the drug is low , but has a long-lasting effect ; generally the efficacy can be maintained for more than 1-2 week per injection . This product has a low binding rate with plasma albumin protein , and is metabolized into non-active product in the liver , kidneys and tissues which is then further excreted by the kidneys . It also has a long-lasting effect upon local injection .

Moreover , topical ointments can also produce a good effect . Clinically triamcinolone acetonide is used for treatment of various skin diseases such as atopic dermatitis , contact dermatitis , seborrheic dermatitis , neurodermatitis , eczema , psoriasis , psoriasis , lichen planus and skin pruritus , as well as bronchial asthma , rheumatoid arthritis , acute sprains , chronic ache in back and legs , frozen shoulder, tenosynovitis , ophthalmic inflammation , oral mucosal congestion , erosion , ulcers , granulomatous cheilitis , and oral mucosa chronic infectious diseases , Furthermore , it can also be used for local injection treatment in keloid , cystic acne , discoid lupus erythematosus , alopecia areata and other small area of damages . Triamcinolone acetonide nasal spray can be used for the prevention and treatment of perennial , seasonal allergic rhinitis , and vasomotor rhinitis . Intra-articular injection of this drug can eliminate inflammation and pain , swelling or can alleviate , pain , stiffness and swelling feeling .

 COA :

Items Specifications Results

Appearance White or practically white, odorless, crystalline powder Conforms

Identification A: IR; B:UV Conforms

Specific rotation +65°~+72° +70°

Loss on drying ≤2.0% 0.19%

Residue on ignition ≤0.5% Conforms

Heavy metals ≤0.0025% Conforms

Assay 97.0%~102.0% 98.8%

Particle size Micronized Conforms