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Antibacterial Pharmaceutical Intermediate CAS 125-46-2 Usnic Acid
Quick Details
Product name: Usnic acid
Other Name (+-)-uanicacid;2,6-diacetyl-1,;2,6-diacetyl-1,2,3,9b-tetrahydro-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3-dione;2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2h,9bh)-dibenzofurandione;3(2H,9bH)-Dibenzofurandione,2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1;9bh)-dibenzofurandione,2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-3(2h;usninsaeure;usno
Original China
CAS 125-46-2
EINECS 231-456-0
Molecular formula C18H16O7
Molecular Weight 344.32
Brand name CQSP steroid
Delivery time within 24 hours upon receipt of payment
Delivery Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS
Purity 99%
Package Discreet and Hidden package according to specific requirement
Appearance Yellow powder
Certification SGS, ISO 9001, KOSHER
Payment Terms Western Union, Money Gram , T/T, Bitcoin
Minimum Order Quantity 10 g
Price Negotiable
Usage antibacterial
Reference FOB Price:$0.32/g
Specification:ISO9001,USP,BP,GMP
Trade Mark:CQSP
Production Capacity:5000kg/month
Shipping: DHL, EMS, FedEx, UPS
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Description:
Usnic acid is a naturally occurring dibenzofuran derivative found in several lichen species. It was first isolated by German scientist W. Knop in 1844 and first synthesized between 1933-1937 by Curd and Robertson.Usnic acid was identified in many genera of lichens including Usnea, Cladonia, Hypotrachyna, Lecanora, Ramalina, Evernia, Parmelia and Alectoria. Although it is generally believed that usnic acid is exclusively restricted to lichens, in a few unconfirmed isolated cases the compound was found in kombucha tea and non-lichenized ascomycetes.
At normal conditions, usnic acid is a bitter, yellow, solid substance.It is known to occur in nature in both the d- and l-forms as well as a racemic mixture. Salts of usnic acid are called usnates (e.g. copper usnate).
Applciation:
1.Lichen extracts containing usnic acid have been utilized in medicine, perfumery, cosmetics, and ecology.
Usnic acid possesses a wide range of interesting biological properties. It is a potent antibiotic effective againstGram-positive bacteria, including Staphylococcus, Streptococcus, and Pneumococcus, other bacteria such asMycobacterium tuberculosis, and some pathogenic fungi. It also exhibits antiviral, antiprotozoal, antimitotic, anti-inflammatory and analgesic activity. Other characteristics, like ultraviolet absorption, preserving properties, antigrowth, antiherbivore and anti-insect properties, have also been demonstrated.
2.Usnic acid has been included as an ingredient in creams, powders, toothpastes, mouthwash, deodorants, hair shampoos and sunscreen products. In some of these preparations, usnic acid is employed as an active principle, in others as a preservative.
3.Usnic acid and its salt form, sodium usniate, have been marketed in the US as an ingredient in food supplements for use in weight reduction, although unsupported by solid scientific proof. These supplements, if taken according to label instructions, can supply daily oral doses of 10-1350 mg for adults.
4.Usnic acid is a major metabolite from a number of lichen and fungal species and is perhaps one of the longest known microbial metabolites, first isolated in 1844. Usnic acid exhibits a broad range of biological activity, indeed it is easier to list the bioassays in which it does not exhibit activity. More often than not, potency is low and of limited value. Usnic acid is an important metabolite for dereplication in discovery research programs.