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Estogen Hormone Raw Powder CAS: 630-56-8 17a-Hydroxyprogesterone
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Product Name: 17a-Hydroxyprogesterone
Synonyms: PREGN-4-ENE-3,20-DIONE HEXANOATE;17-((1-oxohexyl)oxy)-pregn-4-ene-20-dione;17-((1-Oxohexyl)oxy)pregn-4-ene-3,20-dione;17a-hydroxyprogesteronehexanoate;17-alpha-Hexanoyloxypregn-4-ene-3,20-dione;17alpha-Hydroxyprogesterone n-caproate;17-alpha-hydroxyprogesteronen-caproate;17-Hydroxypregn-4-ene-3,20-dione caproate
CAS: 630-56-8
MF: C27H40O4
MW: 428.6
EINECS: 211-138-8
HS Code: 29163920
Shelf life:2 years
Reference FOB Price:$1/g
MOQ:10g
Production Capacity:5000kg/month
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17a-Hydroxyprogesterone Description:
(1). 17α-Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid).
(2). 17α-Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.
(3). The US FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy.
17a-Hydroxyprogesterone Specifications:
Standard:USP31
Items Standard Resutls
Description White or almost white crystalline powder, odorless Conforms
Solubility insoluble in water, solube in ether, slightly soluble in benzene Conforms
Specific Optical Rotation +58°---+64° (1% chloroform Solution) 60.3°
Melting Point about 120 -124 ºC 123ºC
Water ≤0.1% 0.05%
Free N-Caproic Acid ≤0.58% 0.20%
Ordinary Impurities ≤2.0% conforms
Residual Solvents Methanol ≤ 3000PPM 1280PPM
Ethanol≤5000PPM 1500PPM
Dichloromethane ≤ 600PPM 80PPM
Assay 97.0%--103.0% 99.30%
Application:
This medication is used in women who are pregnant with a single baby, and who have delivered a baby too early (preterm) in the past. It is used to help lower the risk of having a preterm baby again. Hydroxyprogesterone is a man-made form of a female hormone (progestin). It is not known how it works to prevent preterm labor.
This medication is not intended to prevent preterm birth in women pregnant with more than one baby (such as twins, triplets). It is also not intended to stop active preterm labor.
Side effects:
Pain, swelling, itching, bruising, or a lump at the injection site may occur. Nausea ordiarrhea may also occur.